Summary

Name CLDN4
Full Name Claudin-4
Synonyms Clostridium perfringens enterotoxin receptor, CPE-R, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein | CPER, CPETR1, WBSCR8
Primary ID O14493
Links - -
Type protein
Relations 1
Function Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation CLDN4 0.491
Publications: 1 Organism: Chlorocebus Aethiops