Name	SOCS2
Full Name	Suppressor of cytokine signaling 2
Synonyms	SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2 \| CIS2, SSI2, STATI2
Primary ID	O14508
Links	- -
Type	protein
Relations	4
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.