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Summary
Name
CDK2AP1
View Modifications
Full Name
Cyclin-dependent kinase 2-associated protein 1
Synonyms
CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor | CDKAP1, DOC1
Primary ID
O14519
Links
-
-
Type
protein
Relations
2
Function
specific inhibitor of the cell-cycle kinase CDK2.
Viewer
Search Tools
Refine search:
by mechanism
none
phosphorylation
binding
by effect
none
unknown
down-regulates activity
by organism:
none
in vitro
by tissue:
none
by cell-line
none
▶
Modifications Tables
CDK2AP1 as Target
Residue
Sequence
Modifier
Effect
Modification
Ser46
LSDYGPPsLGYTQGT
IKBKE
unknown
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
IKBKE
phosphorylation
CDK2AP1
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-264780
Ser46
LSDYGPPsLGYTQGT
in vitro
pmid
sentence
22427660
CDK2AP1 is phosphorylated at a conserved Ser-46 site in the N-terminal "intrinsically disordered" region by IkappaB kinase epsilon.
Publications:
1
Organism:
In Vitro
+
CDK2AP1
down-regulates activity
binding
CDK2
0.452
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-264781
pmid
sentence
22427660
The ubiquitously expressed CDK2AP1 protein is the only known specific inhibitor of CDK2, making it an important component of cell cycle regulation during G1-to-S phase transition.
Publications:
1