3.0
Summary
| Name |  BCKDKView Modifications |
| Full Name | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial |
| Synonyms | Branched-chain alpha-ketoacid dehydrogenase kinase, BCKD-kinase, BCKDHKIN |
| Primary ID | O14874 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | BCKDK | down-regulates 
phosphorylation
|
BCKDHA | 0.593 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Skeletal Muscle, Brain, Heart, Kidney | |||
| + | SRC | up-regulates quantity by stabilization 
phosphorylation
|
BCKDK | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SRC | up-regulates activity
phosphorylation
|
BCKDK | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |