Summary

Name ACLY
Full Name ATP-citrate synthase
Synonyms ATP-citrate (pro-S-)-lyase, ACL, Citrate cleavage enzyme
Primary ID P53396
Links - -
Type protein
Relations 25
Pathways Citric acid cycle - Krebs cycle, Fatty Acid Synthesis
Function Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.

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▶Modifications Tables

Relations


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Regulator Mechanism target score ℹ
+ GSK3Bup-regulates activity img/direct-activation.png phosphorylation ACLY 0.356
Publications: 2
+ AKT