Relation Results

Summary

Name WNT9B
Full Name Protein Wnt-9b
Synonyms Protein Wnt-14b, Protein Wnt-15 | WNT14B, WNT15, WNT14B, WNT15
Primary ID O14905
Links - -
Type protein
Relations 5
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. ...
View More

Viewer

Type: Score: Layout: SPV 
0.2790.20.6070.6130.59SOSTDC1WNT9BCHRNA1FZD3LRP6LRP5

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ SOSTDC1down-regulates activity img/indirect_inhibition.png WNT9B 0.279
Identifier Residue Sequence Organism Cell Line
SIGNOR-242739 Mus musculus
pmid sentence
Our laboratory identified an almost twofold upregulation of sclerostin domain-containing 1 (Sostdc1; also referred to as WISE, USAG-1, ectodin), a dual Bmp/Wnt inhibitor, in postnatal day (P)1 pancreata from transgenic mice misexpressing hepatocyte nuclear factor (Hnf)6 in islet endocrine cells.
Publications: 1 Organism: Mus Musculus
+ WNT9Bup-regulates img/direct-activation.png binding CHRNA1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-195978 Homo sapiens Neuron
pmid sentence
We identified five wnts (wnt9a, wnt9b, wnt10b, wnt11, and wnt16) that are able to stimulate achr clustering, of which wnt9a and wnt11 are expressed abundantly in developing muscles.
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle
+ WNT9Bup-regulates img/direct-activation.png binding FZD3 0.607
Identifier Residue Sequence Organism Cell Line
SIGNOR-132111 Homo sapiens
pmid sentence
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation.
Publications: 1 Organism: Homo Sapiens
+ WNT9Bup-regulates img/direct-activation.png binding LRP6 0.613
Identifier Residue Sequence Organism Cell Line
SIGNOR-163552 Homo sapiens
pmid sentence
We find that wnt9b binds to a different part of the lrp6 extracellular domain
Publications: 1 Organism: Homo Sapiens
+ WNT9Bup-regulates img/direct-activation.png binding LRP5 0.59
Identifier Residue Sequence Organism Cell Line
SIGNOR-132114 Homo sapiens
pmid sentence
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation.
Publications: 1 Organism: Homo Sapiens
a simple tooltip