| + |
ATP6V0E1 | form complex 
binding
|
V-ATPase |
0.554 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277747 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33065002 |
Vesicular- or vacuolar-type adenosine triphosphatases (V-ATPases) are ATP-driven proton pumps comprised of a cytoplasmic V1 complex for ATP hydrolysis and a membrane-embedded Vo complex for proton transfer. They play important roles in acidification of intracellular vesicles, organelles, and the extracellular milieu in eukaryotes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TFEB | up-regulates quantity by expression 
transcriptional regulation
|
ATP6V0E1 |
0.316 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-276534 |
|
|
|
|
| pmid |
sentence |
| 19556463 |
Under aberrant lysosomal storage conditions, TFEB translocated from the cytoplasm to the nucleus, resulting in the activation of its target genes.|Expression analysis of lysosomal genes after TFEB overexpression and silencing. Blue bars show the fold change of the mRNA levels of lysosomal genes in TFEB- versus pcDNA3-transfected cells. |
|
| Publications: |
1 |
| + |
CREB5 | up-regulates quantity by expression
transcriptional regulation
|
ATP6V0E1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253801 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21132541 |
Our result verified CREB5 biological regulation module in the upstream of frontal cortex of HIVE-control patients (MAPKAPK3 activation; DGKG, LY96, TNFRSF11B inhibition) and downstream (ATP6V0E1, CFB, DGKG, MX1, TGFBR3 activation; LGALS3BP, RASGRP3, RDX, STAT1 inhibition), |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
ATP6V0E1
- 
- 