3.0
Summary
| Name |  MAP3K13View Modifications |
| Full Name | Mitogen-activated protein kinase kinase kinase 13 |
| Synonyms | Leucine zipper-bearing kinase, Mixed lineage kinase, MLK | LZK |
| Primary ID | O43283 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
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phosphorylation