3.0
Summary
| Name |  PRPF3View Modifications |
| Full Name | U4/U6 small nuclear ribonucleoprotein Prp3 |
| Synonyms | Pre-mRNA-splicing factor 3, hPrp3, U4/U6 snRNP 90 kDa protein | HPRP3, PRP3 |
| Primary ID | O43395 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CSNK2A1 | up-regulates 
phosphorylation
|
PRPF3 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | USP4 | down-regulates activity 
deubiquitination
|
PRPF3 | 0.501 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRPF19 | up-regulates activity
polyubiquitination
|
PRPF3 | 0.742 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MECP2 | up-regulates activity
binding
|
PRPF3 | 0.271 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Tissue: | Brain | |||
| + | PRPF3 | form complex 
binding
|
U4/U6.U5 snRNP complex | 0.766 |
| Publications: | 1 | Organism: | Homo Sapiens | |