| + |
PITX2 | down-regulates quantity by repression 
transcriptional regulation
|
TBX1 |
0.432 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251870 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20129917 |
Pitx2 activated Tbx4, Tbx15, and Mga and repressed Tbx1, Tbx2, Tbx5, and Tbx6 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TBX1 | up-regulates quantity by expression 
transcriptional regulation
|
FLT4 |
0.313 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251869 |
|
|
Homo sapiens |
Endothelial Cell |
| pmid |
sentence |
| 20439995 |
Tbx1 plays a critical role in lymphatic vessel development and regulates the expression of Vegfr3, a gene that is essential for lymphangiogenesis. Tbx1 activates Vegfr3 transcription in endothelial cells (ECs) by binding to an enhancer element in the Vegfr3 gene. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ASH2L | up-regulates activity 
binding
|
TBX1 |
0.313 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251868 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20463296 |
Tbx1 interacts with Ash2l in both yeast and mammalian cells and Ash2l acts as a transcriptional co-activator in luciferase reporter assays. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
TBX1
- 
- 