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Summary
| Name |  PROM1View Modifications |
| Full Name | Prominin-1 |
| Synonyms | Antigen AC133, Prominin-like protein 1 | PROML1 |
| Primary ID | O43490 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439). |
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phosphorylation
dephosphorylation