3.0
Summary
| Name |  PTPRKView Modifications |
| Full Name | Receptor-type tyrosine-protein phosphatase kappa |
| Synonyms | Protein-tyrosine phosphatase kappa, R-PTP-kappa | PTPK |
| Primary ID | Q15262 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PTPRK |
dephosphorylation
|
EGFR | 0.601 |
| Publications: | 2 | Organism: | Cricetulus Griseus | |
| + | PTPRK | down-regulates activity 
dephosphorylation
|
STAT3 | 0.382 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPRK | down-regulates activity
dephosphorylation
|
PROM1 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PTPRK | up-regulates activity 
dephosphorylation
|
ZNRF3 | 0.361 |
| Publications: | 1 | Organism: | Homo Sapiens | |