4.0
Summary
| Name |  TBC1D4View Modifications |
| Full Name | TBC1 domain family member 4 |
| Synonyms | Akt substrate of 160 kDa, AS160 | AS160, KIAA0603 |
| Primary ID | O60343 |
| Links |  -  -  |
| Type | protein |
| Relations | 7 |
| Function | May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | AKT |
phosphorylation
|
TBC1D4 | 0.2 |
| Publications: | 2 | Organism: | Mus Musculus, Homo Sapiens | |
| + | AKT1 |
phosphorylation
|
TBC1D4 | 0.765 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TBC1D4 | down-regulates 
|
SLC2A4 | 0.667 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AKT2 | down-regulates activity 
phosphorylation
|
TBC1D4 | 0.642 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AKT | down-regulates
phosphorylation
|
TBC1D4 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Muscle | |||
| + | AKT1 | down-regulates
phosphorylation
|
TBC1D4 | 0.765 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Muscle | |||