+ |
RELA | up-regulates quantity by expression
transcriptional regulation
|
IEX-1L |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-59542 |
|
|
Homo sapiens |
|
pmid |
sentence |
9703517 |
Transcription factors of the nuclear factor-kappab/rel (nf-kappab) family may be important in cell survival by regulating unidentified, anti-apoptotic genes. One such gene that protects cells from apoptosis induced by fas or tumor necrosis factor type alpha (tnf), iex-1l, is described here. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NFKB1 | up-regulates quantity by expression
transcriptional regulation
|
IEX-1L |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-59539 |
|
|
Homo sapiens |
|
pmid |
sentence |
9703517 |
Transcription factors of the nuclear factor-kappab/rel (nf-kappab) family may be important in cell survival by regulating unidentified, anti-apoptotic genes. One such gene that protects cells from apoptosis induced by fas or tumor necrosis factor type alpha (tnf), iex-1l, is described here. Its transcription induced by tnf was decreased in cells with defective nf-kappab activation, rendering them sensitive to tnf-induced apoptosis, which was abolished by transfection with iex-1l. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |