Relation Results

Summary

Name IEX-1L
Full Name
Synonyms O75353_HUMAN
Primary ID O75353
Links - -
Type protein
Relations 2
Function

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Type: Score: Layout: SPV 
0.20.2RELAIEX-1LNFKB1

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Relations
Regulator
Mechanism
target
score ℹ
+ RELAup-regulates quantity by expression img/indirect-activation.png transcriptional regulation IEX-1L 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-59542 Homo sapiens
pmid sentence
Transcription factors of the nuclear factor-kappab/rel (nf-kappab) family may be important in cell survival by regulating unidentified, anti-apoptotic genes. One such gene that protects cells from apoptosis induced by fas or tumor necrosis factor type alpha (tnf), iex-1l, is described here.
Publications: 1 Organism: Homo Sapiens
+ NFKB1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation IEX-1L 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-59539 Homo sapiens
pmid sentence
Transcription factors of the nuclear factor-kappab/rel (nf-kappab) family may be important in cell survival by regulating unidentified, anti-apoptotic genes. One such gene that protects cells from apoptosis induced by fas or tumor necrosis factor type alpha (tnf), iex-1l, is described here. Its transcription induced by tnf was decreased in cells with defective nf-kappab activation, rendering them sensitive to tnf-induced apoptosis, which was abolished by transfection with iex-1l.
Publications: 1 Organism: Homo Sapiens
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