3.0
Summary
| Name |  LTN1
|
| Full Name | E3 ubiquitin-protein ligase listerin |
| Synonyms | RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294 | C21orf10, C21orf98, KIAA0714, RNF160, ZNF294 |
| Primary ID | O94822 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875, PubMed:28757607). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). |
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