Name
|
LTN1
|
Full Name |
E3 ubiquitin-protein ligase listerin |
Synonyms |
RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294 | C21orf10, C21orf98, KIAA0714, RNF160, ZNF294 |
Primary ID |
O94822 |
Links |
- - |
Type |
protein |
Relations |
2 |
Function |
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875, PubMed:28757607). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). |