3.0
Summary
| Name |  KIF20AView Modifications |
| Full Name | Kinesin-like protein KIF20A |
| Synonyms | GG10_2, Mitotic kinesin-like protein 2, MKlp2, Rab6-interacting kinesin-like protein, Rabkinesin-6 | MKLP2, RAB6KIFL |
| Primary ID | O95235 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | NEK6 | down-regulates activity 
phosphorylation
|
KIF20A | 0.354 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PPP2R5B | up-regulates activity 
dephosphorylation
|
KIF20A | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AURKB | down-regulates activity
phosphorylation
|
KIF20A | 0.774 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PLK1 | up-regulates activity
phosphorylation
|
KIF20A | |
| Publications: | 1 | Organism: | Homo Sapiens | |