Summary

Name SERPINA1
Full Name Alpha-1-antitrypsin
Synonyms Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1 | AAT, PI
Primary ID P01009
Links - -
Type protein
Relations 1
Function Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.; FUNCTION

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding LRP1 0.14
Publications: 1 Organism: Homo Sapiens