+ |
NfKb-p65/p50 | up-regulates quantity by expression
transcriptional regulation
|
FTH1 |
0.344 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254792 |
|
|
Homo sapiens |
T-lymphoma Cell Line |
pmid |
sentence |
19258503 |
We show that inhibition of constitutively active NF-kappaB causes down-regulation of ferritin heavy chain (FHC) that leads to an increase of free intracellular iron, which, in turn, induces massive generation of ROS. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ATF1 | down-regulates quantity by repression
transcriptional regulation
|
FTH1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253741 |
|
|
Homo sapiens |
|
pmid |
sentence |
17565989 |
Here we found that ATF1 (activating transcription factor 1) is a transcriptional repressor of the ferritin H ARE. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |