Summary

Name MPO
Full Name Myeloperoxidase
Synonyms MPO |
Primary ID P05164
Links - -
Type protein
Relations 3
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png binding MPO 0.25
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding MPO-ANCA 0.2
Publications: 1 Organism: Homo Sapiens
Tissue: Blood Serum
+ down-regulates activity img/direct_inhibition.png oxidation APOA1 0.423
Publications: 1 Organism: Homo Sapiens