| + |
KRT1 | up-regulates quantity 
binding
|
MPO |
0.249 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251886 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17591979 |
CK1 and CK9 specifically bind MPO. MPO is internalized by endothelial cells through a direct interaction with the endothelial surface protein CK1 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KRT1 | up-regulates activity
phosphorylation
|
APC |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251879 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18359618 |
Phosphorylation of this central repeat region of APC significantly enhances its affinity for β-catenin. When the repeats are phosphorylated by the cooperative action of CK1 and GSK3β, the binding interaction is significantly altered and enhanced. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PLAUR | up-regulates activity
binding
|
KRT1 |
0.293 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251880 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 14691569 |
Cytokeratin 1 binds to both gC1qR and u-PAR. Our data suggest that formation of HK (and Factor XII) binding sites along endothelial cell membranes consists of bimolecular com-plexes of gC1qR-cytokeratin 1 and u-PAR-cytokeratin 1, with gC1qR binding being favored. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CRH | up-regulates quantity by expression 
transcriptional regulation
|
KRT1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251882 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15787816 |
CRH also increased AP-1 binding activity, cell granularity, cytokeratin 1 and involucrin expression, and inhibited cytokeratin 14 expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TGFB1 | down-regulates quantity by repression 
transcriptional regulation
|
KRT1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251884 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16258965 |
TGFβ1 and TGFβ2 induce loss of epithelial morphology, cytokeratin, and membrane-associated Zonula Occludens-1 and increase the smooth muscle markers calponin and caldesmon |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
C1QBP | up-regulates activity
binding
|
KRT1 |
0.382 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251881 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 14691569 |
Cytokeratin 1 binds to both gC1qR and u-PAR. Our data suggest that formation of HK (and Factor XII) binding sites along endothelial cell membranes consists of bimolecular com-plexes of gC1qR-cytokeratin 1 and u-PAR-cytokeratin 1, with gC1qR binding being favored. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TGFB2 | down-regulates quantity by repression
transcriptional regulation
|
KRT1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251885 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16258965 |
Immunolocalization of the epithelial marker cytokeratin demonstrates decreased staining by 48 hr after the addition of TGFβ1 or TGFβ2 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
IL1B | down-regulates quantity by repression
transcriptional regulation
|
KRT1 |
0.251 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251883 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17982242 |
IL-1β alone decreased the expression of E-cadherin and cytokeratin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
KRT1
- 
- 