Summary

Name KRT1
Full Name Keratin, type II cytoskeletal 1
Synonyms 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1 | KRTA
Primary ID P04264
Links - -
Type protein
Relations 8
Function May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation KRT1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation KRT1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation KRT1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation APC 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation KRT1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding KRT1 0.31
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding KRT1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png binding MPO 0.14
Publications: 1 Organism: Homo Sapiens