Summary

Name GP1BA
Full Name Platelet glycoprotein Ib alpha chain
Synonyms GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha |
Primary ID P07359
Links - -
Type protein
Relations 4
Function GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png cleavage GP1BA 0.29
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation GP1BA 0.525
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding GPIb-IX-V complex 0.696
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation GP1BA 0.371
Publications: 1 Organism: Homo Sapiens