+ |
WNT2 | up-regulates
binding
|
LRP5 |
0.608 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-131727 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
WNT2 | up-regulates
binding
|
LRP6 |
0.661 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-131730 |
|
|
Homo sapiens |
|
pmid |
sentence |
15578921 |
Wnt proteins bind to the frizzled receptors and lrp5/6 co-receptors, and through stabilizing the critical mediator betBeta-catenin, initiate a complex signaling cascade that plays an important role in regulating cell proliferation and differentiation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SOSTDC1 | down-regulates activity
|
WNT2 |
0.309 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-242724 |
|
|
Mus musculus |
|
pmid |
sentence |
22829579 |
Our laboratory identified an almost twofold upregulation of sclerostin domain-containing 1 (Sostdc1; also referred to as WISE, USAG-1, ectodin), a dual Bmp/Wnt inhibitor, in postnatal day (P)1 pancreata from transgenic mice misexpressing hepatocyte nuclear factor (Hnf)6 in islet endocrine cells. |
|
Publications: |
1 |
Organism: |
Mus Musculus |