| + |
CDK2 | up-regulates activity 
phosphorylation
|
MYBL2 |
0.728 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250734 |
Ser393 |
RGELIPIsPSTEVGG |
|
HEK-293 Cell |
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250735 |
Ser452 |
PVKTLPFsPSQFLNF |
|
HEK-293 Cell |
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250736 |
Thr266 |
TDLDAVRtPEPLEEF |
|
HEK-293 Cell |
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250737 |
Thr405 |
VGGSGIGtPPSVLKR |
|
HEK-293 Cell |
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250739 |
Thr515 |
QKYSMDNtPHTPTPF |
|
HEK-293 Cell |
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250740 |
Thr518 |
SMDNTPHtPTPFKNA |
|
|
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250741 |
Thr520 |
DNTPHTPtPFKNALE |
Homo sapiens |
|
| pmid |
sentence |
| 10593981 |
Ten phosphorylation sites carboxyl-terminal to the DNA-binding domain were identified by this method: threonines at positions 267, 408, 497, 519, 522, and 524 and serines at positions 283, 396, 455, and 581. | Our results indicate that B-Myb can be phosphorylated in a cell-free system by both cyclin A-Cdk2 and cyclin E-Cdk2 complexes. | These data suggest that B-Myb is a target for phosphorylation by cyclin-Cdk2 and that phosphorylation of B-Myb regulates its transcriptional activity. |
|
| Publications: |
7 |
Organism: |
, Homo Sapiens |
| + |
CDK2 | up-regulates
phosphorylation
|
MYBL2 |
0.728 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-62353 |
Ser577 |
RKPGLRRsPIKKVRK |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk5 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-62357 |
Thr444 |
NSLTPKStPVKTLPF |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk3 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-62361 |
Thr487 |
SQKVVVTtPLHRDKT |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk2 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-62365 |
Thr494 |
TPLHRDKtPLHQKHA |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk4 |
|
| Publications: |
4 |
Organism: |
Homo Sapiens |
| + |
CyclinA2/CDK2 | up-regulates
phosphorylation
|
MYBL2 |
0.725 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-217252 |
Ser577 |
RKPGLRRsPIKKVRK |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk5 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-217256 |
Thr444 |
NSLTPKStPVKTLPF |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk3 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-217260 |
Thr487 |
SQKVVVTtPLHRDKT |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk2 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-217264 |
Thr494 |
TPLHRDKtPLHQKHA |
Homo sapiens |
|
| pmid |
sentence |
| 9840932 |
The cell-cycle regulated transcription factor b-myb is phosphorylated by cyclin a/cdk2 at sites that enhance its transactivation properties. we show that b-myb is phosphorylated at thr447, thr490, thr497 and ser581 by cyclin a/cdk4 |
|
| Publications: |
4 |
Organism: |
Homo Sapiens |
| + |
CDK2 |
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Stack trace:
#0 /home/prisca/signor/relation_result.php(2084): implode()
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4.0
MYBL2
- 
- 