Summary

Name ODC1
Full Name Ornithine decarboxylase
Synonyms ODC |
Primary ID P11926
Links - -
Type protein
Relations 6
Pathways Fibroblast: Arginine metabolism and collagen synthesis
Function Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ APCdown-regulates quantity by repression img/direct_inhibition.png transcriptional regulation ODC1 0.271
Publications: 1 Organism: Homo Sapiens
+ ODC1up-regulates quantity img/direct-activation.png chemical modification spermidine 0.8
Publications: 1 Organism: Homo Sapiens
+ ODC1up-regulates quantity img/direct-activation.png chemical modification spermine 0.8
Publications: 2 Organism: Homo Sapiens
+ ODC1down-regulates quantity img/direct_inhibition.png chemical modification L-ornithine 0.8
Publications: 1 Organism: Homo Sapiens
+ ODC1up-regulates quantity img/direct-activation.png chemical modification putrescine 0.8
Publications: 1 Organism: Homo Sapiens