Summary

Name ODC1
Full Name Ornithine decarboxylase
Synonyms ODC |
Primary ID P11926
Links - -
Type protein
Relations 6
Function Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png small molecule catalysis spermine 0.14
Publications: 2 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ down-regulates quantity img/direct_inhibition.png small molecule catalysis L-ornithine 0.22
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ up-regulates quantity img/direct-activation.png small molecule catalysis putrescine 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ up-regulates quantity img/direct-activation.png small molecule catalysis spermidine 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation ODC1 0.14
Publications: 1 Organism: Homo Sapiens