| + |
OSM | up-regulates quantity by expression
transcriptional regulation
|
AHR |
0.342 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-202963 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24127753 |
The il-6-type cytokine oncostatin m induces ahr expression in a stat3-ependent manner in human hepg2 hepatoma cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
OSM | up-regulates
binding
|
LIFR |
0.728 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-19873 |
|
|
Homo sapiens |
Macrophage, Leukemia Cell |
| pmid |
sentence |
| 1536831 |
Oncostatin m binds the high-affinity leukemia inhibitory factor receptor |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | IL6 Signaling |
| + |
OSM | up-regulates
binding
|
IL6ST |
0.751 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-48114 |
|
|
Homo sapiens |
Leukemia Cell |
| pmid |
sentence |
| 9143707 |
Stimulation of cells with the interleukin-6 family of cytokines triggers homo- or hetero-dimerization of gp130. The dimerization of gp130 leads to activation of associated cytoplasmic tyrosine kinases and subsequent modification of transcription factors. Some of these biological activities of il-6 are also often exerted by other cytokines, i.e. Il-11, lif, osm, cntf, and ct-2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | IL6 Signaling |
| + |
OSM | up-regulates
binding
|
OSMR |
0.795 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-141588 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16286453 |
The oncostatin m receptor (osmr) is part of receptor complexes for oncostatin m and interleukin-31. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |