+ |
EFEMP2 | up-regulates activity
binding
|
ELN |
0.575 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-252136 |
|
|
Homo sapiens |
|
pmid |
sentence |
19570982 |
Fibulin-4 directly binds LOX, and this interaction enhances fibulin-4 binding to tropoelastin, thus forming a ternary complex that may be critical for elastin cross-linking. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FBLN5 | up-regulates
binding
|
ELN |
0.753 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-186603 |
|
|
Homo sapiens |
|
pmid |
sentence |
19570982 |
Our data show that fibulin-5 can interact with tropoelastin or with fibrillin-1, implying a chaperone role for fibulin-5 in directing elastin onto microfibrils |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FBLN5 | up-regulates activity
binding
|
ELN |
0.753 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-252137 |
|
|
Homo sapiens |
|
pmid |
sentence |
18267938 |
The binding of tropoelastin fragments to fibulin-5 was directly proportional to their propensity to coacervate. Furthermore, the addition of fibulin-5 to tropoelastin facilitated coacervation. Taken together, the present study shows that fibulin-5 enhances elastic fiber formation in part by improving the self-association properties of tropoelastin. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |