| + |
YWHAE | up-regulates activity 
binding
|
TBP |
0.348 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262834 |
|
|
|
|
| pmid |
sentence |
| 10449590 |
The in vitro binding with general transcription factors TBP and TFIIB together with its nuclear location provide evidence supporting a role for 14-3-3 proteins as transcriptional activators or coactivators when part of a DNA binding complex. |
|
| Publications: |
1 |
| + |
GTF2A2 | up-regulates activity
binding
|
TBP |
0.901 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262591 |
|
|
in vitro |
|
| pmid |
sentence |
| 8626665 |
The general transcription factor IIA (TFIIA) binds to the TATA binding protein (TBP) and mediates transcriptional activation by distinct classes of activators. |Our results show that different activators utilize the general factor TFIIA in unique ways and that TFIIA contributes transcription activation functions in addition to the facilitation of TBP-DNA binding. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
TBP | form complex 
binding
|
SL1 complex |
0.748 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269562 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FOXF2 | up-regulates activity
binding
|
TBP |
0.409 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-220373 |
|
|
in vitro |
|
| pmid |
sentence |
| 9722567 |
The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
TBP | up-regulates quantity by expression 
transcriptional regulation
|
LIN28B |
0.25 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255252 |
|
|
Homo sapiens |
MCF-7 Cell |
| pmid |
sentence |
| 23494474 |
We conclude that the oncoprotein HBXIP as a co-activator of TF II D transactivates Lin28B promoter via directly binding to TBP to upregulate the expression of Lin28B in promotion of proliferation of breast cancer cells, in which Lin28B maintains the high level of HBXIP through suppressing miR-520b in a feedback manner. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MSX1 | down-regulates activity 
binding
|
TBP |
0.399 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-240401 |
|
|
in vitro |
|
| pmid |
sentence |
| 8700832 |
Msx-1 is a potent transcriptional repressor and that this activity is independent of its DNA binding function. Here we show that Msx-1 interacts directly with the TATA binding protein (TBP) but not with several other general transcription factors. This interaction is mediated by the Msx-1 homeodomain, specifically through residues in the N-terminal arm. These same N-terminal arm residues are required for repression by Msx-1, suggesting a functional relationship between TBP association and transcriptional repression. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
ZNF76 | down-regulates activity
binding
|
TBP |
0.4 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-224650 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15280358 |
We identified ZNF76 as a novel transcriptional repressor that targets TBP. ZNF76 interacts with TBP through both its N and C termini. ZNF76 targets TBP for transcriptional repression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BTAF1 | up-regulates activity
binding
|
TBP |
0.71 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263919 |
|
|
Oryctolagus cuniculus |
|
| pmid |
sentence |
| 15509807 |
We present evidence that the NC2alpha subunit interacts with BTAF1. Addition of NC2alpha or the NC2 complex can stimulate the ability of BTAF1 to interact with TBP. |
|
| Publications: |
1 |
Organism: |
Oryctolagus Cuniculus |
| + |
TBP | form complex
binding
|
TFIID |
0.893 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263933 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27096372 |
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which specifically interact with a variety of core promoter DNA sequences. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TBP | form complex
binding
|
TFIIIB |
0.835 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266192 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
Both in yeast and mammalian cells, TFIIIB consists of three subunits: TFIIB-related Brf1, TATA-box binding protein (TBP), common also for the other two RNA polymerases, and Pol III-specific subunit, Bdp1 (Table 1). |
|
| Publications: |
1 |
| + |
HUWE1 | down-regulates quantity
ubiquitination
|
TBP |
0.338 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278696 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26393420 |
Having established that Huwe1 mediates TBP ubiquitination in vitro, we then asked which E2 conjugating enzymes work best with Huwe1 in this reaction.|Upregulation of Huwe1 expression during myogenesis induces TBP degradation and myotube differentiation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
TBP
- 
- 