| + |
PTEN | down-regulates quantity by destabilization 
|
SL1 complex |
0.278 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269645 |
|
|
|
|
| pmid |
sentence |
| 16055704 |
PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex |
|
| Publications: |
1 |
| + |
RRN3 | up-regulates activity 
relocalization
|
SL1 complex |
0.661 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269647 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11250903 |
HRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters|We conclude that hRRN3 functions to recruit initiation-competent Pol I to rRNA gene promoters. The essential role for hRRN3 in linking Pol I to SL1 suggests a mechanism for growth control of Pol I transcription. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
TAF1B | form complex 
binding
|
SL1 complex |
0.844 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269565 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TAF1D | form complex
binding
|
SL1 complex |
0.813 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269563 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TBP | form complex
binding
|
SL1 complex |
0.749 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269562 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TAF1C | form complex
binding
|
SL1 complex |
0.805 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269564 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SL1 complex | up-regulates activity
binding
|
UBTF |
0.664 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269567 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15970593 |
Therefore, we propose that SL1 directs PIC formation, functioning in core promoter binding, RNA polymerase I recruitment, and UBF stabilization and that SL1-promoter complex formation is a necessary prerequisite to the assembly of functional and stable PICs that include the UBF activator in mammalian cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
TAF1A | form complex
binding
|
SL1 complex |
0.824 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269566 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30693017 |
SL1 comprises TBP, TAF1A (also known as TAFI48), TAF1B (also known as TAFI63), TAF1C (also known as TAFI110), and TAF1D (also known as TAFI41) and recruits the RNAP1 complex to induce PIC formation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
SL1 complex