Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-44773 |
|
|
Homo sapiens |
|
pmid |
sentence |
8925404 |
The mammalian tachykinins include substance p, neurokinin a and neurokinin b, which exert their effects by binding to specific receptors. These tachykinin receptors are divided into three types, designated nk1, nk2 and nk3, respectively. The interaction of tachykinin with its receptor activates gq, which in turn activates phospholipase c to break down phosphatidyl inositol bisphosphate into inositol trisphosphate (ip3) and diacylglycerol (dag). |
|