| + |
CGB Family | up-regulates 
binding
|
LHCGR |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-69400 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10446903 |
The ?-Subunit of human choriogonadotropin interacts with the exodomain of the luteinizing hormone/choriogonadotropin receptor |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NR2C2 | up-regulates quantity by expression
transcriptional regulation
|
LHCGR |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266217 |
|
|
Chlorocebus aethiops |
CV-1 Cell |
| pmid |
sentence |
| 10644740 |
Functional analysis showed that EAR2 and EAR3/COUP-TFI repressed the hLHR promoter activity, whereas TR4 activated hLHR gene transcription. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
NR2F1 | down-regulates quantity by repression 
transcriptional regulation
|
LHCGR |
0.281 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266218 |
|
|
Chlorocebus aethiops |
|
| pmid |
sentence |
| 10644740 |
Functional analysis showed that EAR2 and EAR3/COUP-TFI repressed the hLHR promoter activity, whereas TR4 activated hLHR gene transcription. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
Goserelin | up-regulates activity
chemical activation
|
LHCGR |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259162 |
|
|
Homo sapiens |
Prostate Cancer Cell Line |
| pmid |
sentence |
| 11900209 |
LHRH analogues, such as goserelin, reduce circulating concentrations of oestrogen in premenopausal women via an inhibitory effect on the hypothalamic–pituitary–ovarian axis. At the cellular level, LHRH analogues bind to LHRH receptors on pituitary gland cells, an action which causes an initial surge in the secretion of luteinizing hormone (LH). Once bound to ligand, these LHRH receptors form clusters, which are then sequestered within the cell, thereby reducing the number of unoccupied LHRH receptors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NR2F6 | down-regulates quantity by repression
transcriptional regulation
|
LHCGR |
0.31 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266216 |
|
|
Chlorocebus aethiops |
CV-1 Cell |
| pmid |
sentence |
| 10644740 |
Functional analysis showed that EAR2 and EAR3/COUP-TFI repressed the hLHR promoter activity, whereas TR4 activated hLHR gene transcription. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
LHB | up-regulates
binding
|
LHCGR |
0.67 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-70028 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10446903 |
Hcg is a heterodimeric glycoprotein hormone, consisting of a common? -subunit and a hormone-specific ?-Subunit (2). It binds to the lh receptor (lhr). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
LHCGR
- 
- 