Relation Results

Summary

Name NR2F1
Full Name COUP transcription factor 1
Synonyms COUP-TF1, COUP transcription factor I, COUP-TF I, Nuclear receptor subfamily 2 group F member 1, V-erbA-related protein 3, EAR-3 | EAR3, ERBAL3, TFCOUP1
Primary ID P10589
Links - -
Type protein
Relations 9
Function Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) sti ...
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Type: Score: Layout: SPV 
0.20.2460.2740.20.2570.2510.2720.2760.545TWIST2NR2F1ESRRARXRBPCDH19NR2F2TWIST1CREB1LHCGRRXRA

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Relations
Regulator
Mechanism
target
score ℹ
+ TWIST2up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NR2F1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-255506 Homo sapiens HGC-27 Cell
pmid sentence
we performed microarray analysis to compare the gene expression profiles in HGC-27 cells, with or without small interfering RNA (siRNA)-mediated depletion of TWIST. Our results showed that NF1, RAP1A, SRPX, RBL2, PFDN4, ILK, F2R, ERBB3, and MYB were up-regulated, whereas AKR1C2, FOS, GDF15, NR2F1, ATM, and CTPS were down-regulated after TWIST depletion
Publications: 1 Organism: Homo Sapiens
+ ESRRAdown-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation NR2F1 0.246
Identifier Residue Sequence Organism Cell Line
SIGNOR-253795 Homo sapiens Bronchoalveolar Lavage
pmid sentence
In cancer tissue, the expression levels of EAR-2, COUP-TF1, EARgamma, Snail, and Slug decrease, and aromatase expression is then up-regulated through the binding of ERRalpha to S1 and the binding of CREB1 or related factors to CREaro.
Publications: 1 Organism: Homo Sapiens
+ RXRBup-regulates img/direct-activation.png binding NR2F1 0.274
Identifier Residue Sequence Organism Cell Line
SIGNOR-79449 Homo sapiens
pmid sentence
Arp-1/rxr, coup-tfi/rxr, and arp-1/coup-tfi heterodimers bound the fp330-3' site
Publications: 1 Organism: Homo Sapiens
+ NR2F1up-regulates quantity by expression img/direct-activation.png transcriptional regulation PCDH19 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-267223 Mus musculus
pmid sentence
We demonstrated that high expression of COUP-TFI induces MEC cell fate and protocadherin 19 expression. We next demonstrated that COUP-TFI is able to directly bind to a conserved Sp1/COUP-TFI binding site in the Pcdh19 promoter region by chromatin immunoprecipitation (ChIP) (Fig. 6, E and F).
Publications: 1 Organism: Mus Musculus
Tissue: Brain
+ NR2F2up-regulates img/direct-activation.png binding NR2F1 0.257
Identifier Residue Sequence Organism Cell Line
SIGNOR-79443 Homo sapiens
pmid sentence
Arp-1/rxr, coup-tfi/rxr, and arp-1/coup-tfi heterodimers bound the fp330-3' site.
Publications: 1 Organism: Homo Sapiens
+ TWIST1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NR2F1 0.251
Identifier Residue Sequence Organism Cell Line
SIGNOR-255531 Homo sapiens HGC-27 Cell
pmid sentence
we performed microarray analysis to compare the gene expression profiles in HGC-27 cells, with or without small interfering RNA (siRNA)-mediated depletion of TWIST. Our results showed that NF1, RAP1A, SRPX, RBL2, PFDN4, ILK, F2R, ERBB3, and MYB were up-regulated, whereas AKR1C2, FOS, GDF15, NR2F1, ATM, and CTPS were down-regulated after TWIST depletion
Publications: 1 Organism: Homo Sapiens
+ CREB1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation NR2F1 0.272
Identifier Residue Sequence Organism Cell Line
SIGNOR-253792 Homo sapiens Infected Cell
pmid sentence
In cancer tissue, the expression levels of EAR-2, COUP-TF1, EARgamma, Snail, and Slug decrease, and aromatase expression is then up-regulated through the binding of ERRalpha to S1 and the binding of CREB1 or related factors to CREaro.
Publications: 1 Organism: Homo Sapiens
+ NR2F1down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation LHCGR 0.276
Identifier Residue Sequence Organism Cell Line
SIGNOR-266218 Chlorocebus aethiops
pmid sentence
Functional analysis showed that EAR2 and EAR3/COUP-TFI repressed the hLHR promoter activity, whereas TR4 activated hLHR gene transcription.
Publications: 1 Organism: Chlorocebus Aethiops
+ NR2F1up-regulates img/direct-activation.png binding RXRA 0.545
Identifier Residue Sequence Organism Cell Line
SIGNOR-79440 Homo sapiens
pmid sentence
Arp-1/rxr, coup-tfi/rxr, and arp-1/coup-tfi heterodimers bound the fp330-3' site
Publications: 1 Organism: Homo Sapiens
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