Summary

Name PTPRD
Full Name Receptor-type tyrosine-protein phosphatase delta
Synonyms Protein-tyrosine phosphatase delta, R-PTP-delta
Primary ID P23468
Links - -
Type protein
Relations 4
Function Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png dephosphorylation STAT3 0.533
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ down-regulates activity img/direct_inhibition.png dephosphorylation STAT3 0.533
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding PTPRD 0.281
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Synaptic_plasticity 0.7
Publications: 1 Organism: Homo Sapiens