Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-249995 |
|
|
in vitro |
|
pmid |
sentence |
9374536 |
Two isoforms of the inositol 1,4,5-trisphosphate 3-kinase have been identified, the A form and the B form. phosphorylation of isoform A by the cyclic AMP-dependent protein kinase increased activity 1.5-fold, whereas phosphorylation of isoform B decreased activity by 45%. major phosphorylation sites in the protein are Ser119 for PKA. Ser119 in the A isoform is conserved in the B isoform as Ser328 |
|