3.0
Summary
| Name |  ELK4
|
| Full Name | ETS domain-containing protein Elk-4 |
| Synonyms | Serum response factor accessory protein 1, SAP-1, SRF accessory protein 1 | SAP1 |
| Primary ID | P28324 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously. |
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phosphorylation