Summary

Name INPP5B
Full Name Type II inositol 1,4,5-trisphosphate 5-phosphatase
Synonyms EC 3.1.3.36, 75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, 5PTase | OCRL2
Primary ID P32019
Links - -
Type protein
Relations 2
Pathways Macropinocytosis
Function Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events. {ECO:0000269|PubMed:7721860}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding INPP5B 0.46
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity img/direct_inhibition.png chemical modification 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate 0.8
Publications: 1 Organism: Homo Sapiens