Summary

Name CCKAR
Full Name Cholecystokinin receptor type A
Synonyms CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R | CCKRA
Primary ID P32238
Links - -
Type protein
Relations 2
Function Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding GNAQ 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding CCKAR 0.93
Publications: 1 Organism: Homo Sapiens
Tissue: Brain