3.0
Summary
| Name |  ACVRL1
|
| Full Name | Serine/threonine-protein kinase receptor R3 |
| Synonyms | SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I | ACVRLK1, ALK1 |
| Primary ID | P37023 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
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