Summary

Name PCM1
Full Name Pericentriolar material 1 protein
Synonyms PCM-1, hPCM-1
Primary ID Q15154
Links - -
Type protein
Relations 8
Function Required for centrosome assembly and function (PubMed:12403812, PubMed:15659651, PubMed:16943179). Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2 (PubMed:12403812, PubMed:15659651). Required to anchor microtubules to the centrosome (PubMed:12403812, PubMed:15659651). Involved in the biogenesis of cilia (PubMed:20551181, PubMed:24121310).

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Relations

Regulator Mechanism target score ℹ
+ PCM1up-regulates img/direct-activation.png relocalization NIN 0.417
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization CEP250 0.532
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization NEK2 0.4
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization CETN1 0.418
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization PCNT 0.675
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization CETN2 0.511
Publications: 1 Organism: Homo Sapiens
+ MIB1down-regulates img/direct_inhibition.png ubiquitination PCM1 0.378
Publications: 1 Organism: Homo Sapiens
+ PCM1up-regulates img/direct-activation.png relocalization CETN3 0.302
Publications: 1 Organism: Homo Sapiens