Summary

Name SOX3
Full Name Transcription factor SOX-3
Synonyms SOX3_HUMAN
Primary ID P41225
Links - -
Type protein
Relations 2
Function Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png transcriptional regulation SOX3 0.2
Publications: 1 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png binding CTNNB1 0.472
Publications: 1 Organism: Homo Sapiens