3.0
Summary
| Name |  SOX3
|
| Full Name | Transcription factor SOX-3 |
| Synonyms | SOX3_HUMAN |
| Primary ID | P41225 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). |
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