3.0
Summary
| Name |  KCNJ4View Modifications |
| Full Name | Inward rectifier potassium channel 4 |
| Synonyms | HIRK2, HRK1, Hippocampal inward rectifier, HIR, Inward rectifier K(+) channel Kir2.3, IRK-3, Potassium channel, inwardly rectifying subfamily J member 4 | IRK3 |
| Primary ID | P48050 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PKA | up-regulates activity 
phosphorylation
|
KCNJ4 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKCA | down-regulates activity 
phosphorylation
|
KCNJ4 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | EGFR | up-regulates activity
phosphorylation
|
KCNJ4 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |