Summary

Name TDO2
Full Name Tryptophan 2,3-dioxygenase
Synonyms TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase | TDO
Primary ID P48775
Links - -
Type protein
Relations 2
Function Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation TDO2 0.257
Publications: 1
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation TDO2 0.347
Publications: 1