+ |
ARFGEF1 | up-regulates activity
guanine nucleotide exchange factor
|
ARF3 |
0.374 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272148 |
|
|
Homo sapiens |
Hep-G2 Cell |
pmid |
sentence |
14973189 |
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) is an approximately 200-kDa brefeldin A-inhibited guanine nucleotide-exchange protein that preferentially activates ADP-ribosylation factor 1 (ARF1) and ARF3. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ARF3 | up-regulates
|
Vesicle_transport |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272150 |
|
|
|
|
pmid |
sentence |
14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
Publications: |
1 |