| + |
ARF1 | up-regulates 
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272149 |
|
|
|
|
| pmid |
sentence |
| 14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
| Publications: |
1 |
| + |
ARF5 | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272152 |
|
|
|
|
| pmid |
sentence |
| 14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
| Publications: |
1 |
| + |
AP-4 Adaptor complex | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280855 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23167973 |
The adaptor proteins (APs) are a family of five heterotetrameric complexes with important functions in vesicle trafficking. The predominant steady-state localization of a sorting adaptor usually indicates the donor compartment of the mediated transport step, suggesting that AP-4 is involved in sorting at the TGN. The simplest model that emerges from these findings suggests that AP-4 mediates anterograde trafficking between the TGN and an endosomal compartment (Figure 1). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AP-5 Adaptor complex | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280860 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29381698 |
Together, our findings suggest that AP-5 functions in a novel sorting step out of late endosomes, acting as a backup pathway for retromer. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ARF4 | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272151 |
|
|
|
|
| pmid |
sentence |
| 14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
| Publications: |
1 |
| + |
NRZ complex | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265026 |
|
|
|
|
| pmid |
sentence |
| 25364732 |
NRZ complex, which comprises NAG, RINT1, and ZW10, is also involved in Golgi-to-ER retrograde transport, but each component of the complex has diverse cellular functions including endosome-to-Golgi transport, cytokinesis, cell cycle checkpoint, autophagy, and mRNA decay. |
|
| Publications: |
1 |
| + |
ARF3 | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272150 |
|
|
|
|
| pmid |
sentence |
| 14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
| Publications: |
1 |
| + |
ARF6 | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272153 |
|
|
|
|
| pmid |
sentence |
| 14973189 |
ADP-ribosylation factors (ARF) are 20-kDa GTPases of the ras superfamily that regulate vesicular transport in eukaryotic cells. There are three classes of ARFs: class I (ARF1–3), which function in endoplasmic reticulum-Golgi trafficking; the much less studied class II (ARF4–5); and class III (ARF6), with significant roles in endocytotic pathways and cytoskeletal dynamics near the cell surface |
|
| Publications: |
1 |
| + |
COPII vesicle | up-regulates
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265297 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30605680 |
Coat protein complex (COP) II vesicles export newly synthesized secretory proteins from the endoplasmic reticulum (ER) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
Vesicle_transport