Summary

Name POLR2F
Full Name DNA-directed RNA polymerases I, II, and III subunit RPABC2
Synonyms RNA polymerases I, II, and III subunit ABC2, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide, RPABC14.4, RPB14.4, RPB6 homolog, RPC15 | POLRF
Primary ID P61218
Links - -
Type protein
Relations 3
Function DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).

Viewer

Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding RNA Polymerase I 0.897
Publications: 1
+ form complex img/form-complex.png binding RNA Polymerase II 0.873
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding RNA Polymerase III 0.862
Publications: 1 Organism: Homo Sapiens