| + |
RNA Polymerase III | up-regulates quantity 
chemical modification
|
tRNA(Pyl) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269494 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SNAPC | up-regulates activity
binding
|
RNA Polymerase III |
0.496 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280636 |
|
|
|
|
| pmid |
sentence |
| 36369505 |
In eukaryotes, small nuclear RNAs (snRNAs) function in many fundamental cellular events such as precursor messenger RNA splicing, gene expression regulation, and ribosomal RNA processing. The snRNA activating protein complex (SNAPc) exclusively recognizes the proximal sequence element (PSE) at snRNA promoters and recruits RNA polymerase II or III to initiate transcription. |
|
| Publications: |
1 |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Lys) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269490 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3F | form complex 
binding
|
RNA Polymerase III |
0.888 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266128 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Sec) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269495 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Arg) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269481 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Trp) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269498 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Phe) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269492 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Gln) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269485 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(His) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269488 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR2K | form complex
binding
|
RNA Polymerase III |
0.813 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266141 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TFIIIB | up-regulates activity
binding
|
RNA Polymerase III |
0.671 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266181 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9308965 |
Transcription by RNA polymerase III (Pol III) requires multiple general initiation factors that, in isolated form, assemble onto the promoter in an ordered fashion. Here, it is shown that all components required for transcription of the VA1 and tRNA genes, including TFIIIB, TFIIIC, and RNA Pol III, can be coimmunopurified from a HeLa cell line that constantly expresses a FLAG epitope-tagged subunit of human RNA Pol III. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
POLR3H | form complex
binding
|
RNA Polymerase III |
0.869 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266126 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Asp) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269483 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Cys) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269484 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3A | form complex
binding
|
RNA Polymerase III |
0.872 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266133 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3D | form complex
binding
|
RNA Polymerase III |
0.88 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266130 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR2H | form complex
binding
|
RNA Polymerase III |
0.873 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266140 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3K | form complex
binding
|
RNA Polymerase III |
0.831 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266135 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR2L | form complex
binding
|
RNA Polymerase III |
0.843 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266142 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table ​Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Pro) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269493 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Val) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269500 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
transfer RNA |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266143 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
POLR3G | form complex
binding
|
RNA Polymerase III |
0.71 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266127 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3B | form complex
binding
|
RNA Polymerase III |
0.867 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266132 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Gly) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269487 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR1D | form complex
binding
|
RNA Polymerase III |
0.869 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266137 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Asn) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269482 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Ile) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269501 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CRCP | form complex
binding
|
RNA Polymerase III |
0.806 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266134 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Ser) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269496 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3E | form complex
binding
|
RNA Polymerase III |
0.855 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266129 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAF1 | down-regulates activity 
binding
|
RNA Polymerase III |
0.381 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266198 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
The synthesis of transfer RNA (tRNA) is directed by RNA polymerase III (Pol III) specialized in high-level transcription of short DNA templates. Pol III recruitment to tRNA genes is controlled by two general initiation factors, TFIIIB and TFIIIC. |Under stress conditions, tRNA synthesis is negatively regulated by the MAF1 protein, which interacts directly with Pol III. |
|
| Publications: |
1 |
| + |
WICH | up-regulates activity
binding
|
RNA Polymerase III |
0.425 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268829 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16603771 |
We show here that the WICH complex (WSTF-SNF2h) interacts with several nuclear proteins as follows: Sf3b155/SAP155, RNA helicase II/Gualpha, Myb-binding protein 1a, CSB, the proto-oncogene Dek, and nuclear myosin 1 in a large 3-MDa assembly, B-WICH, during active transcription. Our results show that a WSTF-SNF2h assembly is involved in RNA polymerase III transcription, and we suggest that WSTF-SNF2h-NM1 forms a platform in transcription while providing chromatin remodeling. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Glu) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269486 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR1C | form complex
binding
|
RNA Polymerase III |
0.884 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266136 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GTF3A | up-regulates activity
binding
|
RNA Polymerase III |
0.491 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266180 |
|
|
|
|
| pmid |
sentence |
| 9308965 |
At present, it is known that transcription factors TFIIIB, TFIIIC2, TFIIIC1, and TFIIIA (5S gene only) are involved in transcription of tRNA, VA RNA, and 5S RNA genes by human RNA Pol III. |
|
| Publications: |
1 |
| + |
TFIIIC | up-regulates activity
relocalization
|
RNA Polymerase III |
0.491 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266182 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 9308965 |
Transcription by RNA polymerase III (Pol III) requires multiple general initiation factors that, in isolated form, assemble onto the promoter in an ordered fashion. Here, it is shown that all components required for transcription of the VA1 and tRNA genes, including TFIIIB, TFIIIC, and RNA Pol III, can be coimmunopurified from a HeLa cell line that constantly expresses a FLAG epitope-tagged subunit of human RNA Pol III. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
small nuclear RNA |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266144 |
|
|
|
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
| Pathways: | Transcription initiation |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Met) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269491 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Ala) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269480 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Tyr) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269499 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR2E | form complex
binding
|
RNA Polymerase III |
0.893 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266138 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Leu) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269489 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR2F | form complex
binding
|
RNA Polymerase III |
0.871 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266139 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
POLR3C | form complex
binding
|
RNA Polymerase III |
0.886 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266131 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 12391170 |
In this article, we use this proposed nomenclature for the S. cerevisiae subunits as the guide to refer to the human RNA polymerase III subunits, as indicated in Table Table1,1, and consequently the numbering of the human subunits does not always correspond to their decreasing apparent molecular weights. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNA Polymerase III | up-regulates quantity
chemical modification
|
tRNA(Thr) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269497 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27911719 |
RNAPIII is specialized for transcription of short, abundant nonprotein-coding RNA transcripts. In addition to all tRNAs, RNAPIII transcribes the 5S rRNA and other essential RNAs, including the U6 small nuclear RNA (snRNA), the snR52 small nucleolar RNA and the RNA components of the signal recognition particle (SRP1) and RNase P (RPR1) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
B-WICH complex | up-regulates activity
binding
|
RNA Polymerase III |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268841 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 25883140 |
The chromatin-remodelling complex B-WICH, comprised of William syndrome transcription factor, the ATPase SNF2h and nuclear myosin, specifically activates RNA polymerase III transcription of the 5S rRNA and 7SL genes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
RNA Polymerase III
CPX-2393