| + |
PRMT1 | down-regulates 
methylation
|
CNBP |
0.376 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-204958 |
Arg25 |
ECPTGGGrGRGMRSR |
Homo sapiens |
|
| pmid |
sentence |
| 24726729 |
Cnbp interacts with protein arginine methyltransferase prmt1 / r25 or r27 appear to be the major methylation sites in cnbp /arginine methylation of cnbp impedes rna binding |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-204962 |
Arg27 |
PTGGGRGrGMRSRGR |
Homo sapiens |
|
| pmid |
sentence |
| 24726729 |
Cnbp interacts with protein arginine methyltransferase prmt1 / r25 or r27 appear to be the major methylation sites in cnbp /arginine methylation of cnbp impedes rna binding |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
CNBP | down-regulates quantity by repression
transcriptional regulation
|
MYC |
0.309 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261571 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 23774591 |
These data verified that the binding of CNBP with c-myc promoter G-quadruplex can indeed down-regulate its associated gene expression for a certain period of time. This result with human CNBP is somehow consistent with previous reports that c-myc G-quadruplex serves as a silencer of c-myc transcription [7] and CNBP promotes the formation of c-myc G-quadruplex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CNBP
- 
- 