3.0
Summary
| Name |  DYNLL1View Modifications |
| Full Name | Dynein light chain 1, cytoplasmic |
| Synonyms | 8 kDa dynein light chain, DLC8, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase, PIN | DLC1, DNCL1, DNCLC1, HDLC1 |
| Primary ID | P63167 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.; FUNCTION |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PAK1 | down-regulates 
phosphorylation
|
DYNLL1 | 0.386 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Breast | |||
| + | DYNLL1 | down-regulates
binding
|
AMBRA1 | 0.525 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | DYNLL1 | down-regulates activity
gtpase-activating protein
|
RHOA | 0.277 |
| Publications: | 1 | Organism: | Homo Sapiens | |