| + |
PRKCD | down-regulates activity 
phosphorylation
|
CNTNAP1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279260 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19632305 |
Inhibition of PKCdelta increased p190 activity, while PKCdelta overexpression diminished p190 activity.|We further show that PKC\u03b4 was able to phosphorylate and bind distinct domains of p190. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CNTNAP1 | up-regulates activity 
relocalization
|
CNTN1 |
0.628 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269073 |
|
|
Mus musculus |
Sciatic Nerve |
| pmid |
sentence |
| 11069942 |
These results suggest that the targeting of contactin to different axonal domains may be determined, in part, via its association with Caspr. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
PTK6 | up-regulates activity
phosphorylation
|
CNTNAP1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279274 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18829532 |
As a consequence, Brk stimulates p190 and attenuates p120 functions, leading to RhoA inactivation and Ras activation, respectively.|Brk phosphorylates p190 at the Y (1105) residue both in vitro and in vivo, thereby promoting the association of p190 with p120RasGAP (p120). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SRC | down-regulates activity
phosphorylation
|
CNTNAP1 |
0.335 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279572 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11672527 |
If that is the case, then our genetic results support the notion that p190 is negatively regulated by both Src and integrin.|The Src family of tyrosine kinases phosphorylate mammalian p190. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
CNTNAP1
- 
- 