3.0
Summary
| Name |  CCT2View Modifications |
| Full Name | T-complex protein 1 subunit beta |
| Synonyms | TCP-1-beta, CCT-beta | 99D8.1, CCTB |
| Primary ID | P78371 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | AKT |
phosphorylation
|
CCT2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RPS6K | up-regulates 
phosphorylation
|
CCT2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RPS6KA1 | up-regulates
phosphorylation
|
CCT2 | 0.251 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AKT1 |
phosphorylation
|
CCT2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RPS6KB1 |
phosphorylation
|
CCT2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CCT2 | form complex 
binding
|
TRiC | 0.746 |
| Publications: | 1 | Organism: | Homo Sapiens | |